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Xi'an confluore Biological Technology Co., Ltd. is a high-tech enterprise (2022) and technology-based small and medium-sized enterprise (2023) professionally engaged in the research, development, and production of biological detection reagents, bioorthogonal linkers and monodisperse polyethylene glycol raw materials for ADC/PROTACs drugs, and providing solutions for customers.
The company possesses core technologies in products such as bioorthogonal chemistry (DBCO, BCN, TCO, Tz, Azide, Alkyne), monodisperse polyethylene glycol, fluorescent dyes (BODIPY, FAM, FITC, TAMRA, Cyanine, SIR, AF647), protein crosslinkers (Mal, Diazirne), bifunctional chelating agents (DOTA, NOTA, DTPA, H3RESCA, Deferoxamine). The company has applied for 10 invention patents and has obtained authorization for 3. It can provide over 2000 types of core raw materials for biological detection reagent manufacturers and ADC/PROTACs new drug R&D enterprises. The quality and price of the products possess extremely strong competitiveness.
The company has a good reputation, having established long-term cooperative relationships with over 500 domestic pharmaceutical enterprises, and has also established business transactions with companies in France, Germany, South Korea, Spain and other countries. The company upholds the concept of "customer-centricity" and works together with customers to promote the development of the cause of human health!
Confluore Biotechnology consistently focuses on the independent research and development and innovative breakthroughs of high-end biological and chemical reagents, committed to breaking import dependence and creating superior domestic biological reagents to meet the cutting-edge needs of complex biomolecule labeling and controlled release. We newly launch the following new product series, including Biotin Cleavable Series Reagents, DSPE-PEGn-NHS ester, Domestic Substitution Fluorescent Probe Series, Scout Molecules Targeting Cysteine, Multi-functionalized Dendrimer PEG Series, o-Phthalaldehyde Probe Series, and other products, to support the leapfrog upgrading in the fields of life sciences, precision medicine, and advanced imaging. They provide smarter solutions for protein purification, targeted drug development, and molecular diagnostics.
The purity of the product is determined by 1H NMR or HPLC-MS to ensure the quality of the product.
We provide our customers with the best prices through continuous technological innovation.
In order to ensure that customers get products as soon as possible, stock products are shipped within 24 hours. Customized products, usually shipped in two weeks.
We provide professional technical advice to our customers, contact us and we will help you.
DBCO , BCN , PEG modified propyne and azide, S-tetrazine series, TCO and cyclopropene and other excellent bio-orthogonal reaction reagents.
Monodisperse PEG derivatives such as Amino-PEGn-NH2, Amino-PEGn-NHBoc, Amino-PEGn-COOH, NH2O-PEGn-COOH.
NH2-PEG-OH, NH2-PEG-COOH, N3-PEG-COOH, Me-PEG-OH, Me-PEG-N3, Me-PEG-COOH, Me-PEG-NH2, Bn-PEG-OH, THP- PEG-OH, etc., monodisperse PEG derivatives with PEG units>12.
Monodisperse, end-functionalized poly(propylene-co-butylene) glycols and random/gradient/block-functionalized poly(ethylene-co-propylene-co-butylene) glycols are prepared via controlled anionic ring-opening polymerization followed by quantitative end-group transformation, affording terminal –NH₂, –COOH, maleimide (MA), maleate (Mal), azide and other clickable moieties. Tailored segmental statistics (random, gradient or block) confer superior thermodynamic miscibility. The materials are engineered for high-crosslink-density waterborne polyurethanes, site-specific drug/protein conjugation, biodegradable elastomers and photocurable 3-D printing networks, enabling precise synergy of mechanical performance, degradation profile and tailored functionality.
NH2-PEG-NH2、NH2-PEG-COOH、NHBoc-PEG-NH2、NHFmoc-PEG-NH2、NH2-PEG-SH、mPEG-NH2、mPEG-COOH 等功能化高分子聚乙二醇。
PEG-NH-PEG、 PEG-Boc-PEG、 PEG-Mal-PEG、 PEG-N-Me-PEG、 PEG-Fluorescein-PEG、 PEG-Biotin-PEG、 PEG-S-PEG、 PEG-SO2-PEG 树枝状单分散PEG。
Charged MTS reagents、Neutral MTS reagents、Spin labelled MTS reagents、Fluorescent labelled reagents 等 MTS 试剂。
DSBSO Crosslinker is a bifunctional, membrane permeable, and enriched sulfoxide containing crosslinker, which is used to analyze protein protein interaction (PPI) by cross-linking mass spectrometry (XL-MS). It will also be a useful proteomics tool for finding protein targets that target "non drug" proteins.
Pyrene, BODIPY, fluorescein, rhodamine and cyanine dyes and their derivatives.
ICG-COOH、ICG-NHS、ICG-amine、ICG-azide、ICG-alkyne、ICG-DBCO、ICG-Tz、ICG-TCO、ICG-Mal、Sulfo-ICG-COOH、Sulfo-ICG-amine、Sulfo-ICG-DBCO、Sulfo-ICG-azide、Sulfo-ICG-azide、Sulfo-ICG-alkyne、Sulfo-ICG-DBCO .
Functional dyes such as membrane potential monitoring and cell tracking are dyes used in medical research and cell culture. After it enters the cell membrane, the dye diffuses on the entire cell membrane, and the entire cell membrane can be stained at the optimal concentration. Before the dye enters the cell membrane, the fluorescence is very weak. When combined with the cell membrane, the fluorescence intensity is greatly enhanced. This type of dye has a high quenching constant and excited state lifetime.
The SiR fluorescent dye replaces the oxygen atoms of the rhodamine nucleus with silicon atoms, making it have the advantages of traditional rhodamine fluorescent dyes, and can also redshift the fluorescence wavelength to the near-infrared band, which is a good solution to the traditional rhodamine The short fluorescence wavelength meets the requirements of near-infrared biofluorescence imaging.
FD-1080, Flav-7, IR-1048 carboxylic acid, amine, azide, alkyne, DBCO, tetrazine, Mal and other click chemical labeled near-infrared second-region dyes.
Azido-Val-Cit-PAB-PNP、MAl-Val-Cit-PAB-PNP、DBCO-Val-Cit-PAB-PNP、BCN-Val-Cit-PAB-PNP、TCO-Val-Cit-PAB-PNP
FAPI-2, FAPI-2 TFA, FAPI-03, FAPI-4, FAPI-05, FAPI-06, FAPI-07, FAPI-08, FAPI-09, FAPI-11, FAPI-12, FAPI-14, FAPI-15.
AT-dye is a common fluorescent dye. It can be used as a fluorescent label and molecular probe for a series of biomolecules such as proteins and nucleic acids. Its spectrum covers the range from ultraviolet light to near-infrared light, and it is the most complete fluorescent label. Compared with other dyes, it has excellent light stability and brightness in the red spectral region.
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AF-dyes is a major breakthrough in fluorescent labeling reagents, including a series of excellent dyes for near ultraviolet, visible light and near infrared spectra. These reagents can be used for labeling and positioning tissues, cells, and biomolecules in biomedical research. Its excitation light and emission light spectrum cover most of the visible light and part of the infrared spectrum, so it is suitable for most fluorescence microscopes.
Small Molecule Probe mainly include: UV-Tracer probes, Huaxi-Fluor probes, and cysteine-targeting detection molecules, which have become new fluorescent probes in recent years. Our company has a series of UV-Tracer probes, HF688[a], HF685[a], HF645[b], HF645-2OH[b], HF546[b] probes, KB02yne, and KB05yne probes to choose from.
Methylene Blue (MB) derivatives, stable in perchlorate form, are key nucleic acid dyes in biochemistry. Built on 3,7 - dimethylamino - phenothiazine - 5 -ium, they undergo redox, substitution, coupling, or click chemistry to gain functional groups. Retaining MB’s photoelectric activity, low toxicity, and redox reversibility, they show improved targeting, absorption range, metabolic stability, and bioconjugation ability via structural changes. These derivatives are widely used in medicine, bioimaging, materials chemistry, and environmental engineering as nucleic acid dyes.
Carboxyl, amino and succinimidyl ester derivatives of BHQ-1, BHQ-2, and BHQ-3.
Acridine salts, strontium complexes, and strontium complexes.
Amine reactive activity, carboxyl reactive activity, carbonyl reactive activity, water soluble and cleavable biotin labeling reagent.
A maleimide derivative, a mercapto derivative, and a diazoxide compound used for photocrosslinking.
Click on chemically labeled amino acids, sugars, phospholipids.
Pomalidomide、(S,R,S)-AHPC、BG、GGG、(S)-Di-tert-butyl-2-(3-((S)-6-amino-1-(tert-butoxy)-1-oxohexan-2-yl)ureido)pentanedioate and other Small molecule target head labeling.
DOTA, NOTA, H3RESCA, MAG3, DTPA, Deferoxamine, NTA, Octaaminocryptands and other bifunctional chelating agent derivatives, used in the research and development of medical diagnosis and treatment reagents.
Functional macromolecular polymers are polymer materials with chemically active functions.
9,10-anthracene 2-2(methylene malonic acid, three butterfly -9-2 formaldehyde, N-benzyl chlorine quinine, 4-fluoro-7-nitrobenzene and miscellaneous-1,3-2-oxygen-1, sell like hot cakes, and other biochemical reagents.
Custom catalog products of analogs and derivatives. In addition, natural product derivatives and bioactive small molecules can also be customized.
